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يمنع استخدام الدواء دون استشارة الطبيب المختص في الحالات الآتية:PDE3 is included in control of cardiac contractility. Sildenafil is just about ten-fold as potent for PDE5 when compared to PDE6, an enzyme found in the retina that's involved in the phototransduction pathway with the retina. This r